| Name | Recombinant Human KPNA2 (N-6His) |
| Purity | Greater than 95% as determined by reducing SDS-PAGE |
| Endotoxin level | <1 EU/µg as determined by LAL test. |
| Construction | Recombinant Human Karyopherin Subunit Alpha-2 is produced by our E.coli expression system and the target gene encoding Met1-Phe529 is expressed with a 6His tag at the N-terminus. |
| Accession # | P52292 |
| Host | E.coli |
| Species | Human |
| Predicted Molecular Mass | 60.04 KDa |
| Buffer | Supplied as a 0.2 μm filtered solution of 20mM Glycine, 8% Sucrose, 20% Glycerol, 150mM NaCl, 0.1% Tween80, 2mM DTT, pH 3.0. |
| Form | Liquid |
| Shipping | The product is shipped on dry ice/polar packs.Upon receipt, store it immediately at the temperature listed below. |
| Stability&Storage | Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles. |
Alternative Names
Importin Subunit Alpha-2; Karyopherin Subunit Alpha-2; RAG Cohort Protein 1; SRP1-Alpha; KPNA2; RCH1; SRP1
Background
Karyopherin Subunit α-2 (KPNA2) belongs to the importin alpha family. KPNA2 is widely expressed in many tissues and contains an N-terminal hydrophilic region, a hydrophobic central region composed of 10 repeats, and a short hydrophilic C-terminus. KPNA2 interacts with the NLSs of DNA helicase Q1 and SV40 T antigen and may be involved in the nuclear transport of proteins. KPNA2 also may play a role in V(D)J recombination. KPNA2 functions in nuclear protein importantly as an adapter protein for nuclear receptor KPNB1.
Note
For Research Use Only , Not for Diagnostic Use.
