CDT2 Rabbit Polyclonal Antibody

CDT2 Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab00293 Category: Polyclonal Antibody Tags: , , , , , ,

Datasheet

Summary

Production Name

CDT2 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

DTL

Alternative Names

CDW1; DCAF2; Dtl; L2DTL; RAMP

Gene ID

51514

SwissProt ID

Q9NZJ0

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 79 kDa; Observed MW: 91 kDa

 

Background

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).

 

Research Area

Cell Biology

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