Summary
| Production Name | Phospho-YAP (Ser127) Rabbit Polyclonal Antibody |
| Description | Rabbit Polyclonal Antibody |
| Host | Rabbit |
| Application | WB,IHC-P,ICC/IF |
| Reactivity | Human,Mouse,Rat |
Performance
| Conjugation | Unconjugated |
| Modification | Phosphorylated |
| Isotype | IgG |
| Clonality | Polyclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | YAP1 |
| Alternative Names | YAP1; YAP65; Yorkie homolog; 65 kDa Yes-associated protein; YAP65 |
| Gene ID | 10413 |
| SwissProt ID | P46937 |
Application
| Dilution Ratio | WB: 1:500-1:1000 IHC: 1:50-1:100 ICC: 1:100-1:200 |
| Molecular Weight | Calculated MW: 54 kDa; Observed MW: 65 kDa |
Background
YAP (Yes-associated protein, YAP65) was identified based on its ability to associate with the SH3 domain of Yes. Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Research Area
Signal Transduction
