Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200 SKU: APRab00953 Category: Polyclonal Antibody Tags: , , , , , , , ,

Datasheet

Summary

Production Name

Phospho-GSK3 (Tyr279/Tyr216) Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC,ICC/IF

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Phosphorylated

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

GSK3A

Alternative Names

Serine/threonine-protein kinase GSK3A

Gene ID

2931

SwissProt ID

P49840

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Molecular Weight

Calculated MW: 51 kDa; Observed MW: 46,51 kDa

 

Background

GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase.

 

Research Area

Neuroscience

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