Junctional Adhesion Molecule 1 Rabbit Polyclonal Antibody

Junctional Adhesion Molecule 1 Rabbit Polyclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200 SKU: APRab03724 Category: Polyclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Junctional Adhesion Molecule 1 Rabbit Polyclonal Antibody

Description

Primary antibody

Host

Rabbit

Application

WB,IHC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Purification

Affinity Chromatography

 

Immunogen

Gene Name

F11R

Alternative Names

F11R; JAM1; JCAM; Junctional adhesion molecule A; JAM-A; Junctional adhesion molecule 1; JAM-1; Platelet F11 receptor; Platelet adhesion molecule 1; PAM-1; CD321

Gene ID

50848

SwissProt ID

Q9Y624

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 33 kDa; Observed MW: 33 kDa

 

Background

Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.

 

Research Area

Cardiovascular

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