FEN1 (1E7) Mouse Monoclonal Antibody-Mouse Monoclonal Antibody-EnkiLife-Recombinant Proteins,Antibodies,Kits,Cell Biology

FEN1 (1E7) Mouse Monoclonal Antibody

Summary

Production Name	FEN1 (1E7) Mouse Monoclonal Antibody
Description	Primary antibody
Host	Mouse
Application	WB,IP
Reactivity	Human,Mouse,Rat

Performance

Conjugation	Unconjugated
Modification	Unmodified
Isotype	IgG1
Clonality	Monoclonal Antibody
Form	Liquid
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Buffer	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Purification	Affinity Purified

Immunogen

Gene Name	FEN1
Alternative Names	FEN1; RAD2; Flap endonuclease 1; FEN-1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1
Gene ID	2237
SwissProt ID	P39748

Application

Dilution Ratio	WB: 1/500-1/1000 IP: 1/20
Molecular Weight	Calculated MW: 43 kDa; Observed MW: 43 kDa

Background

Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA.

Research Area

Epigenetics and Nuclear Signaling