Cytokeratin 17 (8C6) Mouse Monoclonal Antibody

Cytokeratin 17 (8C6) Mouse Monoclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: AMM00866 Category: Mouse Monoclonal Antibody Tags: , , , , ,

Datasheet

Summary

Production Name

Cytokeratin 17 (8C6) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,ICC/IF,IP

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

KRT17

Alternative Names

Keratin; type I cytoskeletal 17; Cytokeratin-17; CK-17; Keratin-17; K17

Gene ID

3872

SwissProt ID

Q04695

 

Application

Dilution Ratio

WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 48 kDa

 

Background

Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state (By similarity). Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway (By similarity). Involved in tissue repair.

 

Research Area

Signal Transduction