Smad3 (4H4) Mouse Monoclonal Antibody

Smad3 (4H4) Mouse Monoclonal Antibody

Size1:50μl Price1:$150
Size2:100μl Price2:$280
Size3:500μl Price3:$1200
SKU: AMM00899 Category: Mouse Monoclonal Antibody Tags: , , , ,

Datasheet

Summary

Production Name

Smad3 (4H4) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB,IHC

Reactivity

Human,Rat,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

SMAD3

Alternative Names

SMAD3; MADH3; Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3

Gene ID

4088

SwissProt ID

P84022

 

Application

Dilution Ratio

WB: 1/500-1/1000 IHC: 1/50-1/100

Molecular Weight

Calculated MW: 48 kDa; Observed MW: 48 kDa

 

Background

Smad3 transcription factor phosphorylated and activated by TGF-beta-type receptors. A receptor-regulated Smad (R-smad). Binds directly to consensus DNA-binding elements in the promoters of target genes. In mouse required for establishemnt of the mucosal immune response and proper development of skeleton.

 

Research Area

Signal Transduction