Summary
| Production Name | Hsc70 (5C2) Mouse Monoclonal Antibody |
| Description | Primary antibody |
| Host | Mouse |
| Application | WB,IHC |
| Reactivity | Human,Rat,Mouse |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purified |
Immunogen
| Gene Name | HSPA8 |
| Alternative Names | Heat shock cognate 71 kDa protein (Heat shock 70 kDa protein 8) |
| Gene ID | 3312 |
| SwissProt ID | P11142 |
Application
| Dilution Ratio | WB: 1/500-1/1000 IHC: 1/50-1/100 |
| Molecular Weight | Calculated MW: 71 kDa; Observed MW: 71 kDa |
Background
Acts as a repressor of transcriptional activation. Inhibits the transcriptional coactivator activity of CITED1 on Smad-mediated transcription. Chaperone. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing.
Research Area
Signal Transduction
