Summary
| Production Name | XRCC1 (3F6) Mouse Monoclonal Antibody |
| Description | Mouse Monoclonal Antibody |
| Host | Mouse |
| Application | WB |
| Reactivity | Human |
Performance
| Conjugation | Unconjugated |
| Modification | Unmodified |
| Isotype | IgG1 |
| Clonality | Monoclonal Antibody |
| Form | Liquid |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Purification | Affinity Purification |
Immunogen
| Gene Name | XRCC1 |
| Alternative Names | XRCC1; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1 |
| Gene ID | 7515 |
| SwissProt ID | P18887 |
Application
| Dilution Ratio | WB: 1:500-1:1000 |
| Molecular Weight | Calculated MW: 69 kDa; Observed MW: 82 kDa |
Background
XRCC1 acts as a scaffold protein to coordinate DNA abasic site repair through interaction with several other repair proteins. At least eight XRCC1 protein partners have been identified, including the polynucleotide kinase PNK, DNA ligase III, poly (ADP-ribose) polymerase, and PCNA.
Research Area
Epigenetics and Nuclear Signaling
