TAK1 (3G1) Mouse Monoclonal Antibody

TAK1 (3G1) Mouse Monoclonal Antibody

Size1:50μl Price1:$168
Size2:100μl Price2:$300
Size3:500μl Price3:$1200
SKU: AMM03860 Category: Mouse Monoclonal Antibody Tags: , , ,

Datasheet

Summary

Production Name

TAK1 (3G1) Mouse Monoclonal Antibody

Description

Primary antibody

Host

Mouse

Application

WB

Reactivity

Human,Mouse,Rat,Monkey

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG2b

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Affinity Purified

 

Immunogen

Gene Name

MAP3K7

Alternative Names

MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1

Gene ID

6885

SwissProt ID

O43318

 

Application

Dilution Ratio

WB: 1/500-1/1000

Molecular Weight

Calculated MW: 67 kDa; Observed MW: 67,78 kDa

 

Background

Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.

 

Research Area

Signal Transduction