Recombinant Human IL-1RAPL1 (C-Fc)

Recombinant Human IL-1RAPL1 (C-Fc)

Size1:10μg price1:$280
Size2:50μg price2:$775
Size3:500μg price3:$3200 SKU: PHH1955 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human IL-1RAPL1 (C-Fc)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Interleukin-1 Receptor Accessory Protein-like 1 is produced by our Mammalian expression system and the target gene encoding Leu19-Thr357 is expressed with a human IgG1 Fc tag at the C-terminus.

Accession #

Q9NZN1

Host

Human Cells

Species

Human

Predicted Molecular Mass

68 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Interleukin-1 Receptor Accessory Protein-Like 1; IL-1-RAPL-1; IL-1RAPL-1; IL1RAPL-1; Oligophrenin-4; Three Immunoglobulin Domain-Containing IL-1 Receptor-Related 2; TIGIRR-2; X-Linked Interleukin-1 Receptor Accessory Protein-Like 1; IL1RAPL1; OPHN4

 

Background

Interleukin-1 receptor accessory protein-like 1, also known as IL1RAPL1, can be detected at low levels in heart, skeletal muscle, ovary, skin, amygdala, caudate nucleus, corpus callosum, hippocampus, substantia nigra and thalamus. IL1RAPL1 functions as a homodimer, it interacts with NCS1, PTPRD. This interaction is PTPRD-splicing-dependent and induces pre- and post-synaptic differentiation of neurons and is required for IL1RAPL1-mediated synapse formation. During dendritic spine formation, it can bidirectionally induce pre- and post-synaptic differentiation of neurons by trans-synaptically binding to PTPRD.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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