Recombinant Human MOG (C-6His)

Recombinant Human MOG (C-6His)

Size1:10μg price1:$89
Size2:50μg price2:$248
Size3:500μg price3:$1680 SKU: PEH1173 Category: Target Proteins Tags: ,

Datasheet

Name

Recombinant Human MOG (C-6His)

Purity

Greater than 95% as determined by reducing SDS-PAGE

Endotoxin level

<1 EU/µg as determined by LAL test.

Construction

Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.

Accession #

Q16653

Host

E.coli

Species

Human

Predicted Molecular Mass

15.2 KDa

Buffer

Lyophilized from a 0.2 μm filtered solution of 20 mM Glycine-HCl, 50 mM NaCl, 10% Trehalose, 0.05% Tween80, pH3.5.

Form

Lyophilized

Shipping

The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.

Stability&Storage

Store at ≤-70°C, stable for 6 months after receipt.Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

Reconstitution

Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

 

 

 

Alternative Names

Myelin-Oligodendrocyte Glycoprotein; MOG; MOG(1-125)

 

Background

Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein, which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals, namely experimental autoimmune encephalomyelitis (EAE), in rodents and monkeys.

 

Note

For Research Use Only , Not for Diagnostic Use.

 

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