Summary
Performance
Immunogen
Application
Background
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013],catalytic activity:ATP = 3',5'-cyclic AMP + diphosphate.,cofactor:Binds 2 magnesium ions per subunit.,function:This is a membrane-bound, calcium-inhibitable adenylyl cyclase.,similarity:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.,similarity:Contains 2 guanylate cyclase domains.,
Research Area
Purine metabolism;Calcium;Chemokine;Oocyte meiosis;Vascular smooth muscle contraction;Gap junction;GnRH;Progesterone-mediated oocyte maturation;Melanogenesis;Dilated cardiomyopathy;
