PHF1 Rabbit Polyclonal Antibody($99/20μL)

PHF1 Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$118
Size3:100μL Price2:$220
Size4:200μL Price3:$380
Application:WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PHF1 SKU: APRab16062 Category: Polyclonal Antibody Tags: , , , , , , , , ,

Summary

Production Name

PHF1 Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

PHF1

Alternative Names

PHF1; PCL1; PHD finger protein 1; Protein PHF1; Polycomb-like protein 1; hPCl1

Gene ID

5252

SwissProt ID

O43189

 

Application

Dilution Ratio

WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:10000, IF-P/IF-F/ICC/IF 1:50-200

Molecular Weight

62kDa

 

Background

This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],function:Transcriptional repressor. May promote methylation of histone H3 on 'Lys-27' by the PRC2/EED-EZH2 complex.,similarity:Contains 2 PHD-type zinc fingers.,subcellular location:Localizes specifically to the promoters of numerous target genes.,subunit:Interacts with CHMP1 (By similarity). Interacts with the PRC2 complex.,tissue specificity:Highest levels in heart, skeletal muscle, and pancreas, lower levels in brain, placenta, lung, liver and kidney.,

 

Research Area

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