PARP1 (10C2) Mouse Monoclonal Antibody

PARP1 (10C2) Mouse Monoclonal Antibody

Size1:50μL Price1:$150
Size2:100μL Price2:$280
Size3:200μL Price3:$520
Application:WB,IHC-P
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PARP1 SKU: AMM03588 Category: Mouse Monoclonal Antibody Tags: , , , , , , ,

Datasheet

Summary

Production Name

PARP1 (10C2) Mouse Monoclonal Antibody

Description

Mouse Monoclonal Antibody

Host

Mouse

Application

WB,IHC-P

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG1

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Purification

Ascitic Fluid

 

Immunogen

Gene Name

PARP1

Alternative Names

PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Gene ID

142

SwissProt ID

P09874

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100

Molecular Weight

Calculated MW: 113 kDa; Observed MW: 116 kDa

 

Background

Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

 

Research Area

Epigenetics and Nuclear Signaling

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