OSR1 (phospho Thr185) Rabbit Polyclonal Antibody($99/20μL)

OSR1 (phospho Thr185) Rabbit Polyclonal Antibody($99/20μL)

Size1:20μL Price1:$99
Size2:50μL Price1:$128
Size3:100μL Price2:$230
Size4:200μL Price3:$380
Application:WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA
Reactivity:Human,Mouse
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:OXSR1 SKU: APRab05138 Category: Polyclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

OSR1 (phospho Thr185) Rabbit Polyclonal Antibody

Description

Rabbit Polyclonal Antibody

Host

Rabbit

Application

WB,IHC-P,IF-P,IF-F,ICC/IF,ELISA

Reactivity

Human,Mouse

 

Performance

Conjugation

Unconjugated

Modification

Phospho Antibody

Isotype

IgG

Clonality

Polyclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.

Purification

Affinity purification

 

Immunogen

Gene Name

OXSR1

Alternative Names

OXSR1; KIAA1101; OSR1; Serine/threonine-protein kinase OSR1; Oxidative stress-responsive 1 protein

Gene ID

9943

SwissProt ID

O95747

 

Application

Dilution Ratio

WB 1:500-1:2000, IHC-P 1:100-1:300, ELISA 1:10000, IF-P/IF-F/ICC/IF 1:50-200

Molecular Weight

65kDa

 

Background

The product of this gene belongs to the Ser/Thr protein kinase family of proteins. It regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. [provided by RefSeq, Jul 2008],catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:By autophosphorylation on threonine.,function:Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds to and phosphorylates PAK1. Interacts with chloride channel proteins SLC12A6 isoform 2, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress. Binds to and phosphorylates RELL1, RELL2 AND RELT.,tissue specificity:Ubiquitously expressed in all tissue examined.,

 

Research Area

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