NCE2 Rabbit Monoclonal Antibody

NCE2 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Size3:200μL Price3:$520
Application:WB,IHC-F,IHC-P,ICC/IF
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:UBE2F SKU: AMRe02307 Category: Rabbit Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

NCE2 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB,IHC-F,IHC-P,ICC/IF

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal Antibody

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Purification

Affinity Purification

 

Immunogen

Gene Name

UBE2F

Alternative Names

NCE2; NEDD8 carrier protein UBE2F; NEDD8 protein ligase UBE2F; NEDD8-conjugating enzyme 2

Gene ID

140739

SwissProt ID

Q969M7

 

Application

Dilution Ratio

WB: 1:500-1:1000 IHC: 1:50-1:100 IF: 1:50-1:200

Molecular Weight

Calculated MW: 21 kDa; Observed MW: 21 kDa

 

Background

Accepts the ubiquitin-like protein NEDD8 from the UBA3-NAE1 E1 complex and catalyzes its covalent attachment to other proteins. The specific interaction with the E3 ubiquitin ligase RBX2, but not RBX1, suggests that the RBX2-UBE2F complex neddylates specific target proteins, such as CUL5.

 

Research Area

Epigenetics and Nuclear Signaling

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