PARP1 Rabbit Monoclonal Antibody

PARP1 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Application:WB, IHC-P, ICC/IF, FC
Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:PARP1 SKU: AMRe86274 Category: Rabbit Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

PARP1 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB, IHC-P, ICC/IF, FC

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification

Affinity Purification

 

Immunogen

Gene Name

PARP1

Alternative Names

PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1

Gene ID

142

SwissProt ID

P09874

 

Application

Dilution Ratio

WB: 1:1000-1:5000 IHC-P: 1:100-1:200 ICC/IF: 1:100 FC: 1:20-1:50

Molecular Weight

Calculated MW:113 kDa; Observed MW:116,24 kDa

 

Background

This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008]

 

Research Area

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