SUN2 Rabbit Monoclonal Antibody

SUN2 Rabbit Monoclonal Antibody

Size1:50μL Price1:$188
Size2:100μL Price2:$338
Application:WB, IHC-P, ICC/IF, FC
Reactivity:Human,Mouse,Rat
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge). See other 26 conjugates.
Gene Name:SUN2 SKU: AMRe86251 Category: Rabbit Monoclonal Antibody Tags: , , , , , , , ,

Summary

Production Name

SUN2 Rabbit Monoclonal Antibody

Description

Rabbit Monoclonal antibody

Host

Rabbit

Application

WB, IHC-P, ICC/IF, FC

Reactivity

Human,Mouse,Rat

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

IgG

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Purification

Affinity Purification

 

Immunogen

Gene Name

SUN2

Alternative Names

UNC84B

Gene ID

25777

SwissProt ID

Q9UH99

 

Application

Dilution Ratio

WB: 1:1000-1:5000 IHC-P: 1:200-1:1000 ICC/IF: 1:200-1:2000 FC: 1:20-1:50

Molecular Weight

Calculated MW:80 kDa; Observed MW:80 kDa

 

Background

SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1; MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity (summary by Haque et al., 2010 [PubMed 19933576]).[supplied by OMIM, Nov 2010]

 

Research Area

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