ACLY Mouse Monoclonal Antibody

ACLY Mouse Monoclonal Antibody

Size1:50μL Price1:$168
Size2:100μL Price2:$300
Application:WB,IHC,ICC,FC,ELISA

Reactivity:Human,Mouse,Rat,Monkey,Rabbit
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:ACLY
SKU: AMM81201 Category: Mouse Monoclonal Antibody Tags: , , , , , , , , , , ,

Summary

Production Name

ACLY Mouse Monoclonal Antibody

Description

Mouse Monoclonal Antibody

Host

Mouse

Application

WB,IHC,ICC,FC,ELISA

Reactivity

Human,Mouse,Rat,Monkey,Rabbit

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Purified antibody in PBS with 0.05% sodium azide

Purification

Affinity Purification

 

Immunogen

Gene Name

ACLY

Alternative Names

ACL; ATPCL; CLATP

Gene ID

47

SwissProt ID

P53396

 

Application

Dilution Ratio

WB:1:500-1:2000,IHC:1:100-1:500,ICC:1:50-1:500,FC:1:200-1:400,ELISA:1:10000

Molecular Weight

125kDa

 

Background

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.


 

Research Area