ZBTB7B Mouse Monoclonal Antibody

ZBTB7B Mouse Monoclonal Antibody

Size1:50μL Price1:$168
Size2:100μL Price2:$300
Application:WB,IHC,ICC,ELISA

Reactivity:Human
Conjugate:Unconjugated
Optional conjugates: Biotin, FITC (free of charge).
See other 26 conjugates.

Gene Name:ZBTB7B
SKU: AMM80819 Category: Mouse Monoclonal Antibody Tags: , , , , , ,

Summary

Production Name

ZBTB7B Mouse Monoclonal Antibody

Description

Mouse Monoclonal Antibody

Host

Mouse

Application

WB,IHC,ICC,ELISA

Reactivity

Human

 

Performance

Conjugation

Unconjugated

Modification

Unmodified

Isotype

Mouse IgG1

Clonality

Monoclonal

Form

Liquid

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Buffer

Ascitic fluid containing 0.03% sodium azide.

Purification

Affinity Purification

 

Immunogen

Gene Name

ZBTB7B

Alternative Names

THPOK; ZFP67; ZBTB15; c-Krox; hcKrox; ZNF857B; DKFZp686G01254; ZBTB7B

Gene ID

51043

SwissProt ID

O15156

 

Application

Dilution Ratio

WB:1:500-1:2000,IHC:1:200-1:1000,ICC:1:200-1:1000,ELISA:1:10000

Molecular Weight

58kDa

 

Background

ZBTB7B is a transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors (thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. ZBTB7B is a transcriptional repressor of the collagen COL1A1 and COL1A2 genes. It may also function as a repressor of fibronectin and possibly other extracellular matrix genes.

 

Research Area