DUS2_HUMAN   Q9NX74


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UniProt:Q9NX74

Recommended name:tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

EC number:EC:1.3.1.91

Alternative names:(Dihydrouridine synthase 2) (Up-regulated in lung cancer protein 8) (URLC8) (tRNA-dihydrouridine synthase 2-like) (hDUS2)

Cleaved into:

GeneID:54920

Gene names  (primary ):DUS2

Gene names  (synonym ):DUS2L

Gene names  (ORF ):

Length:493

Mass:55050

Sequence:MILNSLSLCYHNKLILAPMVRVGTLPMRLLALDYGADIVYCEELIDLKMIQCKRVVNEVLSTVDFVAPDDRVVFRTCEREQNRVVFQMGTSDAERALAVARLVENDVAGIDVNMGCPKQYSTKGGMGAALLSDPDKIEKILSTLVKGTRRPVTCKIRILPSLEDTLSLVKRIERTGIAAIAVHGRKREERPQHPVSCEVIKAIADTLSIPVIANGGSHDHIQQYSDIEDFRQATAASSVMVARAAMWNPSIFLKEGLRPLEEVMQKYIRYAVQYDNHYTNTKYCLCQMLREQLESPQGRLLHAAQSSREICEAFGLGAFYEETTQELDAQQARLSAKTSEQTGEPAEDTSGVIKMAVKFDRRAYPAQITPKMCLLEWCRREKLAQPVYETVQRPLDRLFSSIVTVAEQKYQSTLWDKSKKLAEQAAAIVCLRSQGLPEGRLGEESPSLHKRKREAPDQDPGGPRAQELAQPGDLCKKPFVALGSGEESPLEGW

Tissue specificity:Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level). {ECO:0000269|PubMed:15994936}.

Induction:

Developmental stage:

Protein families:Dus family, Dus2 subfamily