NETO1_MOUSE   Q8R4I7


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UniProt:Q8R4I7

Recommended name:Neuropilin and tolloid-like protein 1

EC number:

Alternative names:(Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 1)

Cleaved into:

GeneID:246317

Gene names  (primary ):Neto1

Gene names  (synonym ):Btcl1

Gene names  (ORF ):

Length:533

Mass:60242

Sequence:MIYGRSLFHIIASLIILHSSGATKKGTEKQITPETQKSVQCGTWTKHAEGGVFTSPNYPSKYPPDRECVYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEVRDGPFGFSPIIGRFCGQQNPPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKDLGVLKPLPACEFEMGGPEGIVESIQILKEGKASASEAVDCKWYIRAPPRSKIYLRFLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMWADEGSRNSRFQMLFTSFQEPPCEGNTFFCHSNMCINNTLVCNGLQNCVYPWDENHCKEKRKTSLLDQLTNTSGTVIGVTSCIVIILIIVSVIVQIKQPRKKYVQRKSDFDQTVFQEVFEPPHYELCTLRGTGATADFADVAEDFENYHKLRRSSSKCIHDHHCGSQLSSAKGSRSNLSTRDASILAEIPTQPVKPLIPPVNRRNILVMKHNYSQDAADACDIDEIEEVPTTSHRLSRHEKSVQRFCLIGSLSKHESEYNTTRV

Tissue specificity:Expressed only in brain. Present throughout the central nervous system. Highly expressed in the hippocampal CA3 region, olfactory bulb and tubercle, caudate putamen, and neocortex in the adult brain. {ECO:0000269|PubMed:12810072, ECO:0000269|PubMed:15464227, ECO:0000269|PubMed:19243221}.

Induction:

Developmental stage:Observed restrictively in brain throughout embryonic and postnatal stages. Expression pattern in brain slightly changes from 13 dpc to postnatal day 21 (P21). Expressed in both cerebrum and cerebellum throughout P0 to P35. In the cerebrum expression reached a plateau at P14 while expression in the cerebellum remains constant throughout all postnatal stages. {ECO:0000269|PubMed:12810072, ECO:0000269|PubMed:15464227}.

Protein families:


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