SMBT2_MOUSE Q5DTW2
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UniProt:Q5DTW2
Recommended name:Scm-like with four MBT domains protein 2
EC number:
Alternative names:
Cleaved into:
GeneID:
Gene names (primary ):Sfmbt2
Gene names (synonym ):Kiaa1617
Gene names (ORF ):
Length:938
Mass:105981
Sequence:MERYLPVSKKRNSSSSLEKITGSANGNGTLYSEEDTNLEENDFSWGDYLEETGTRAVPHVSFRHVEISIRSNFQPGMKLEVANKNNPDTYWVATIITTCGQLLLLRYCGYGEDRRADFWCDVIIADLHPVGWCTQNNKVLRPPDAIKDKYSDWTDFLIRELTGSRTAPANLLEGPLRGKGPIDLITVDSLIELQDSQNPFQYWIVSVTENVGGRLRLRYVGLEHTESYDRWLFYLDYRLRPIGWCQENKYRMDPPSDLYYLKLPFEWKCALEKALVLAAESPLPMEVFKDHADLQSHFFTVGMRLETLHISDPFHIYPASVTKVFNSKFFQVAIDDLRPEADKPTMLCHADSLGILPVQWCLKNGVNLAPPKGYSGQDFNWVDYHKQRQAEEAPHFCFKNAFSRGFSKNMKLEAVNPVNPGEVCVATVVSVKGRLLWLHLEGLETPMPDIIVDMDSMDIFPVGWCEANSYPLTTPYKASSKSKRKTVHFKMEKQLLSPVPIEKIPHELCLLPPQMDSPVGAINAKYCCPQLFVNHRCFSGPFLNKGRISELPQSVGPGMCVLVLKEILTLITNAAYKPGRVLRELQLVEDPEWNSQEEILKAKYGGKTYRAVVKIVRTADQVMNFCRQVCAKLECCPNLLSPVLISETCPENCSVHTKTRYTYYYGKRRRVIQSSLRVSNIETPPKSTRRRKRRKSVYVQKRRKSAIVVPAGVPAGVPAGVPEDIPAGIPEGIPASIPESIPEGIPESLPEAIPESIPKGSAQKTEQEKRETLDTARKKTGYHGPAYQTDTSAAQVPFARPRRAVTLRRNSEALKRPPVERARRVRTVPTTASSNNRVKGPLVRIVKPEDSSQSDEEKLILESNPLEWSVTDVVRFIKLTDCAPLARIFQEQDIDGQALLLLTLPTVQECMELKLGPAIKLCHQIERVKVAFYAQYAS
Tissue specificity:Expressed in testis and, at much lower levels, in ovary. {ECO:0000269|PubMed:18024232}.
Induction:
Developmental stage:Overall, expression is high in extraembryonic tissues, and low in somatic tissues. Expression starts between 8-cell and blastocyst stages. At 7.5 dpc, highly expressed in the ectoplacental cone and, at much lower levels, in the embryonic and extraembryonic ectoderm. At 14.5 dpc, highly expressed in placenta and, at much lower levels, in the yolk sac. Expression in other tissues, including brain, heart, liver, kidney, gut and genital ridges, is very low. Expressed preferentially from the paternal allele in blastocysts, in various tissues at 7.5 dpc, as well as in yolk sac and placenta at 11.5 and 14.5 dpc. Biallelically expressed in brain and other somatic tissues at 11.5 and 14.5 dpc. {ECO:0000269|PubMed:18024232}.
Protein families: