TSYL2_MOUSE   Q7TQI8


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UniProt:Q7TQI8

Recommended name:Testis-specific Y-encoded-like protein 2

EC number:

Alternative names:(TSPY-like protein 2) (CASK-interacting nucleosome assembly protein) (Differentially-expressed nucleolar TGF-beta1 target protein)

Cleaved into:

GeneID:52808

Gene names  (primary ):Tspyl2

Gene names  (synonym ):Cinap Dentt DXBwg1396e Tspx

Gene names  (ORF ):

Length:677

Mass:77671

Sequence:MDRPDEGPPAKTPRLSSSEPRQRDLPPPPPPPLQRLPLPPPQQRPRPQEETEAAQVLADMRGVGPTLPPPLPYVILEEGGIRAYFTLSAESPGWDHAMESGFGEAPSTGIMETLPSSEISGGSLAIDFQVAEPSSLGEKALETCSLGGWGPQMLVGPKRKEEAIIIVEDEDEDDKESVRRRQRRRRRRRKQRKAKESRERSAQRMESILQALESIQMDLEAVNIKAGKAFLRLKRKFIQMRRPFLERRDLIIQHIPGFWVKAFLNHPRISILINQRDRDIFRYLTNLQVQDLRHISMGYKMKLYFQTNPYFTNMVIVKEFQRNRSGRLVSHSTPIRWHRGQEPQAYNRRSHDTRESFFNWFSNHSLPEADRIAEIIKNDLWVNPVRYYMRRGGYRSSRKKQHGKERAKNQYEMVIMEDAHDHYAIEDILSDISEIDEITDNETIHDIKISDFMETTDYFETTDNEVTDANENLCDSENPDHSEGYNTKITDNKGSVAANPDDNSDDPEEKNTYDSEDSNSEKADGDNTTLRDNQQVTNIQDSSDSDNGDEGSDDEDDDGNEGDNEGSDDDDDDNEGSDDDDRDIRYYKNGPEVFDKALDNRTNQNDYEEEVELISEDSVEEEEETSEEASQLSEDSYEDERIYGEERSEVNSEDSDIQEVLPVPKAWASLGKKGKIG

Tissue specificity:Present at high levels in the pituitary gland and at moderate levels in adrenal gland, brain, testis and ovary. In brain, expressed both in mature neurons and progenitor cells (at protein level). {ECO:0000269|PubMed:12112471, ECO:0000269|PubMed:15241014, ECO:0000269|PubMed:16374801}.

Induction:By TGFB1 or serum in pituitary cell lines (at protein level). {ECO:0000269|PubMed:12112471}.

Developmental stage:Present widely throughout embryogenesis. Present in developing brain from 10.5 dpc to P7 (at protein level). {ECO:0000269|PubMed:12619135, ECO:0000269|PubMed:16374801}.

Protein families:Nucleosome assembly protein (NAP) family


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