SPA3G_MOUSE Q5I2A0
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UniProt:Q5I2A0
Recommended name：Serine protease inhibitor A3G
EC number：
Alternative names：(Serpin A3G) (Serine protease inhibitor 2A) (Serpin 2A)
Cleaved into：
GeneID：20715
Gene names (primary )：Serpina3g
Gene names (synonym )：Spi2A
Gene names (ORF )：
Length：440
Mass：49021
Sequence：MAGVSPAVFGCPDVTLGRNTAVREVQENVTSVDSLTLVSSNTDFAFSLYRKLVLKNPDENVVFSPFSICTALALLSLGAKSNTLKEILEGLKFNLTETPEPDIHQGFRYLLDLLSQPGNQVQISTGSALFIEKHLQILAEFKEKARALYQAEAFTADFQQPLKATKLINDYVSNHTQGKIKELISGLKESTLMVLVNYIYFKGKWKNPFDPNDTFKSEFYLDEKRSVIVSMMKTGYLTTPYFRDEELSCTVVELKYTGNASAMFILPDQGRMQQVEASLQPETLRKWKNSLKPRMIHELRLPKFSISTDYSLEHILPELGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGMAGVGCCAVFDFLEIFFNRPFLMIISDTKAHIALFMAKVTNPERSMNFPNGEGASSQRLESKRLCFGDPLCLIGQ
Tissue specificity：Expressed in bone marrow (particularly hematopoietic stem cells), heart, kidney, liver, lung, skeletal muscle, spleen, testis, thymus and T-cells. {ECO:0000269|PubMed:11438738, ECO:0000269|PubMed:15638460, ECO:0000269|PubMed:8978283}.
Induction：Induction during apoptosis requires NF-kappa-B, a heterodimer of RELA- and NFKB1. {ECO:0000269|PubMed:14517268}.
Developmental stage：T-cell specific expression rises during the differentiation of CD8 T-cell progenitors into memory CD8 T-cells. {ECO:0000269|PubMed:15311278}.
Protein families：Serpin family