UCMA_MOUSE   Q14BU0


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UniProt:Q14BU0

Recommended name:Unique cartilage matrix-associated protein

EC number:

Alternative names:(Upper zone of growth plate and cartilage matrix associated protein)

Cleaved into:Unique cartilage matrix-associated protein C-terminal fragment (Ucma-C) (Gla-rich protein) (GRP)

GeneID:68527

Gene names  (primary ):Ucma

Gene names  (synonym ):

Gene names  (ORF ):

Length:138

Mass:16579

Sequence:MSWRRVILLSSLLALVLLCMLQEGTSASVGSRQAAAEGVQEGVKQKIFMQESDASNFLKRRGKRSPKSRDEVNAENRQRLRDDELRREYYEEQRNEFENFVEEQRDEQEERTREAVEQWRQWHYDGLYPSYLYNRQNI

Tissue specificity:Predominantly expressed in resting chondrocytes. {ECO:0000269|PubMed:18156182}.

Induction:Expression inhibited by TGFB1, and weakly inhibited by BMP2. {ECO:0000269|PubMed:19819238}.

Developmental stage:Transiently expressed in the developing mouse skeleton between day 13.5 dpc of embryonic development and 5 months of postnatal development. Absent in undifferentiated mesenchymal cells. Isoforms 1 and 3 are significantly increased with the onset of chondrogenesis, whereas Isoforms 2 and 4 are detected at a later stage. {ECO:0000269|PubMed:18156182, ECO:0000269|PubMed:19819238}.

Protein families:UCMA family


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